Colchicine pericarditis treatment

There have been reports of myopathy and rhabdomyolysis with the concomitant administration of colchicine and simvastatin in patients with renal impairment.
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pIf you are taking this medication to prevent attacks of pain caused by familial Mediterranean feverthe usual dose is 1.2 to 2.4 milligrams dailyThe total dose may be taken once daily or divided into two doses a dayYour doctor may need to adjust your dose to control your symptoms or if you have side effects./ppBecause of the increased incidence of decreased renal function in the elderly populationand the higher incidence of other co-morbid conditions in the elderly population requiring the use of other medicationsreducing the dosage of colchicine when elderly patients are treated with colchicine should be carefully considered./ppColchicine capsules are a prescription medication used to prevent gout flares in adults./ppAdvise the patient to read the FDA-approved patient labelingMedication Guide/ppNeuromuscular toxicity and rhabdomyolysis have been reported from chronic treatment with colchicine in therapeutic dosesespecially in combination with other drugs known to cause this effectPatients with impaired renal function and elderly patientseven those with normal renal and hepatic functionare at increased riskOnce colchicine treatment is ceasedthe symptoms generally resolve within 1 week to several months./p

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